Endocrine Abstracts

Background: Elevated TSH concentration should be assessed and treated with caution because of the possibility of transient thyroid dysfunction, or, in rare cases, measurement interference. We describe a case with a rare cause of elevated TSH level in a 39-year-old mother and her four children.Case Summary: A 39-year-old lady was referred with a long history of high serum TSH ranging between 18.9 to 38.7 (reference interval 0.4-4.0 mU/l) with FT4 concentr...

Introduction: Type 1 diabetes is an autoimmune condition resulting in insulin deficiency. Surveillance of other autoimmune disorders such as coeliac disease and hypothyroidism is common practice due to their higher co association. We describe a case of a 14 year old girl with 2 rarer autoimmune conditions; primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD)Case summary: A 14 year old girl presented ...

Introduction: Diabetic Ketoacidosis is a life threatening emergency. BSPED has updated their guideline with changes in the fluid management (bolus dose for shock, de-escalate early use of inotropes, percentage dehydration in moderate DKA and maximum weight)Aims: To determine the clinical features and outcome of new presentations of DKA in 0–16 year age range and audit fluid managementM...

Introduction: Congenital hypothyroidism is caused by abnormal development or function of the thyroid gland. Early detection through heel prick screening and treatment prevents irreversible adverse neuro developmental outcome. The national screening program for congenital hypothyroidism in the UK has extremely low false positive rates. We describe 4 siblings with falsely raised TSH related to maternally transmitted macroTSH.Case s...